abstract：:The characterisation of adrenal lesions is a common radiological dilemma. Incidental adrenal lesions are commonly detected with computed tomography (CT), and lesion characterisation is critical. The prevalence of incidental adrenal lesions has been reported to be 2.3% at autopsy and 0.5-2% with abdominal CT. Such lesi...

journal_title：Minerva endocrinologica

authors： Welsh SJ,Khan S

更新日期：2009-06-01 00:00:00

abstract：:According to the literature, the prevalence of papillary thyroid microcarcinoma (PTMC) is increasing. To date, PMTC account for up to 30% of all differentiated thyroid cancers. Patients with PTMC have an excellent prognosis with a normal life expectancy. Because of the differential definitions of the PTMC, the therape...

journal_title：Minerva endocrinologica

authors： Riemann B,Schober O

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:Anaplastic thyroid cancer (ATC) is a rare aggressive tumor arising from the follicular cells of the thyroid gland (as does well differentiated thyroid cancer, WDTC), but ATC cells do not retain any of the biological features of the original follicular cells, such as uptake of iodine and synthesis of thyroglo...

journal_title：Minerva endocrinologica

authors： Chiacchio S,Lorenzoni A,Boni G,Rubello D,Elisei R,Mariani G

更新日期：2008-12-01 00:00:00

abstract：:Neuroendocrine tumours (NET) are relatively rare neoplasms affecting principally the gastroenteropancreatic tract, but with potential ubiquitary location, as the neural crest cells, origin of this group of tumours, are dispersed in various organs and tissues. After the discovery of somatostatin receptors (SSTR) over-e...

journal_title：Minerva endocrinologica

authors： Lopci E,Nanni C,Rampin L,Rubello D,Fanti S

更新日期：2008-09-01 00:00:00

abstract：:Notwithstanding recent neuroendocrinological and neuroradiological findings, about 40% of carriers of pituitary adenoma still reach clinical observation and, consequently, the surgeon, in the stage of suffering from extrasellar extension to a varying degree, especially when the volumetric growth of the lesion is not a...

journal_title：Minerva endocrinologica

authors： Russo A

更新日期：2006-09-01 00:00:00

abstract：AIM:Patients with differentiated thyroid carcinoma (DTC) are closely monitored during the first decade after diagnosis. At intervals of 1-2 years withdrawal of suppressive doses of T(4) is recommended in order to check thyroglobulin (Tg) levels under increased TSH. T(4) therapy is usually withdrawn for 5 weeks (during ...

journal_title：Minerva endocrinologica

authors： Chrisoulidou A,Pazaitou-Panayiotou K,Kaprara A,Platoyiannis D,Lafaras C,Boudina M,Georgiou E,Drimonitis A,Bischiniotis T,Vainas I

更新日期：2006-06-01 00:00:00

abstract：:The normal growth and development of the prostate requires the presence and action of androgens, which are also known risk factors in the origins of benign and malignant prostate disease. Paradoxically, the incidence of prostate disease increases with age when serum androgen levels are in decline and emerging evidence...

journal_title：Minerva endocrinologica

authors： Ellem SJ,Risbridger GP

更新日期：2006-03-01 00:00:00

abstract：:This review concerns the relation between most frequent thyroid gland diseases and diabetes mellitus in adult patients. Special attention is paid to autoimmune thyroiditis, Graves' disease, thyroid autoimmunity in pregnant diabetic women, and iodine metabolism. We focused on mechanisms leading to coexistence of both e...

journal_title：Minerva endocrinologica

authors： Vondra K,Vrbikova J,Dvorakova K

更新日期：2005-12-01 00:00:00

abstract：:Loss of estrogens or androgens causes bone loss by increasing the rate of bone remodeling, and also causes an imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts. Conversely, treatment with androgens, as well as estrogens, maintains cancellous...

journal_title：Minerva endocrinologica

authors： Lindberg MK,Vandenput L,Movèrare Skrtic S,Vanderschueren D,Boonen S,Bouillon R,Ohlsson C

更新日期：2005-03-01 00:00:00

abstract：:Acromegaly is a rare and chronic disease that, in the majority of cases, is due to the presence of a benign growth hormone (GH)-producing tumor of the pituitary. In the past, the diagnosis of acromegaly was established basically on physical changes, and only the patients with a severe clinical picture were brought to ...

journal_title：Minerva endocrinologica

authors： Ferone D,Resmini E,Bocca L,Giusti M,Barreca A,Minuto F

更新日期：2004-12-01 00:00:00

abstract：:The presence of islet cell autoantibodies (ICA), and especially of glutamic acid decarboxylase autoantibodies (GAD65Ab), in patients with non-insulin-dependent diabetes mellitus identifies the so-called latent autoimmune diabetes in the adult (LADA). LADA patients have an increased risk for developing insulin deficien...

journal_title：Minerva endocrinologica

authors： Falorni A

更新日期：2003-12-01 00:00:00

abstract：:Patients and animals with poorly controlled or uncontrolled diabetes present with diurnal hypersecretion of glucocorticoids and altered regulation of the hypothalamo-pituitary-adrenocortical (HPA) axis. Although some of these changes are reversed with insulin replacement therapy, neuroendocrine function is not always ...

journal_title：Minerva endocrinologica

authors： Chan O,Inouye K,Riddell MC,Vranic M,Matthews SG

更新日期：2003-06-01 00:00:00

abstract：:In health, growth hormone (GH) is secreted in a circadian rhythm with superimposed pulsatility. Temporal fluctuations of hormone concentrations are essential for physiological action, and loss of diurnal rhythm is important in the development of disease. GH feedback occurs through the hypothalamus and involves neurope...

journal_title：Minerva endocrinologica

authors： White HD,Ahmad AM,Vora JP

更新日期：2003-03-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development. Decreased GHRH secretion and/or action leads to impairment of this process and somatotrope hypoplasia in both humans and experimental animals. Excessive GHRH...

journal_title：Minerva endocrinologica

authors： Frohman LA,Kineman RD

更新日期：2002-12-01 00:00:00

abstract：:Hyperhomocysteinemia is a well-established risk factor for cardiovascular disease. Various factors, both modifiable and non-modifiable, interact with the homocysteine metabolism and determine the plasma homocysteine concentrations. These include genetic abnormalities, age, sex and various nutritional and hormonal dete...

journal_title：Minerva endocrinologica

authors： Asnani S,Desouza C,Homan J,Murthy SN,McNamara DB,Fonseca V

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:The study evaluates the circadian rhythm of melatonin in relation to sex and age and identified contemporary alterations in the secreton of some hypophyseal hormones, suggesting that melatonin may exert a modulatory action on the latter. METHODS:The melatonin metabolite (6-hydroxymelatonin sulfate) was assa...

journal_title：Minerva endocrinologica

authors： Pallotti S,Nordio M,Giuliano S

更新日期：2002-06-01 00:00:00

abstract：:Steroid hormones mediate pleiotropic cellular processes involved in metabolism, cellular proliferation, and differentiation. The ability of the cell to respond to its hormonal environment is transduced by nuclear receptors (NRs) that bind both hormone and DNA. Hence, NRs represent a link between the external hormonal ...

journal_title：Minerva endocrinologica

authors： Amanatullah DF,Zafonte BT,Pestell RG

更新日期：2002-03-01 00:00:00

abstract：:Small cell lung cancer (SCLC) is a biologically aggressive tumor with a low long-term survival rate. SCLC is highly responsive to chemotherapy and surgery has a very limited role in its treatment because the disease is usually widely disseminated at the diagnosis. Good results from surgery have been reported in the sm...

journal_title：Minerva endocrinologica

authors： Puma F,Urbani M,Santoprete S,Ricci F,Sanguinetti A,Vinci D,Ottavi P,Porcaro G,Daddi G

更新日期：2001-12-01 00:00:00

abstract：:The authors present 6 cases of carotid glomus tumours referred to their attention over the past 10 years. Their experience shows that colour ultrasonography (using both morphological and functional evaluation) is the diagnostic key for defining the treatment of paraganglioma. More recent experience highlights the role...

journal_title：Minerva endocrinologica

authors： De Falco M,Sperlongano P,Parmeggiani D,Pisaniello D,Parmeggiani U

更新日期：2001-12-01 00:00:00

abstract：:A number of studies have been carried out over the past year to characterise the physiological functions and possible therapeutic applications of somatostatin (sst). Somatostatin is one of the most widespread peptides in the body and it fulfils a very wide spectrum of actions in the various organs and tissues. The aim...

journal_title：Minerva endocrinologica

authors： Florio T,Schettini G

更新日期：2001-09-01 00:00:00

abstract：:Many hormones and some neuropeptides and neurotransmitters play a key role in regulating numerous lymphoid cell functions. In particular, somatostatin (ss), substance P (sp) and vasoactive intestinal polypeptide (vip) appear to be involved in numerous regulating mechanisms of cell activities in the immune system under...

journal_title：Minerva endocrinologica

authors： Ferone D,Lombardi G,Colao A

更新日期：2001-09-01 00:00:00

abstract：:A 49 year-old woman with anaplastic thyroid carcinoma came, for the first time, to our clinic with an enlarged supraclavicular lymph node. Ten years earlier she received a diagnosis of benign nodular goiter and has been followed up with ultrasonography, which never demonstrated any enlargement of her thyroid nodule an...

journal_title：Minerva endocrinologica

authors： Vescini F,Di Gaetano P,Vigna E,Pascoli A,Cacciari M

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:The surgical approach to Differentiated Thyroid Carcinoma (DTC) is controversial. Aim of this study is to evaluate the opportunity of total thyroidectomy as treatment of choice for DTC in children. METHODS:We examined the tumor features at diagnosis, the complications of surgery and the clinical outcome in ...

journal_title：Minerva endocrinologica

authors： Iurato MP,Scollo C,Belfiore A,Pellegriti G,Salice P,Pezzino V,Giuffrida D

更新日期：2000-06-01 00:00:00

abstract：:The authors take the case of a neuroendocrine tumour of the cecum as the starting point for an analysis of the anatomopathological and diagnostic-therapeutic aspects of these neoplasms. Furthermore, the authors underline that neuroendocrine tumours (NET) of the colon represent an extremely rare nosological entity and ...

journal_title：Minerva endocrinologica

authors： Bonomi M,De Cesare A,Atella F,Angelini M,Graziano P,Piat G

更新日期：1999-09-01 00:00:00

abstract：:A 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node...

journal_title：Minerva endocrinologica

authors： Cossu ML,Palermo M,Coppola M,Fais E,Ruggiu M,Tanda F,Cossu Rocca P,Noya G

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Whether Doppler ultrasonography (DU) may be of help in characterizing thyroid nodes is still under debate: both good and unsatisfactory results have been claimed, either in evaluating the presence of malignancy or in identifying hyperfunctional structures. METHODS:In this paper, the scintigraphic and Dopple...

journal_title：Minerva endocrinologica

authors： Lupi A,Cerisara D,Orsolon P,De Antoni G,Vianello Dri A

更新日期：1999-03-01 00:00:00

abstract：:Medullary thyroid carcinoma arises from the C cells, which produce a characteristic hormone, calcitonin. At present, surgery is the main treatment modality. Medullary thyroid carcinoma is usually treated with total thyroidectomy and with removal of nodes in the central portion of the neck and upper mediastinum. Cervic...

journal_title：Minerva endocrinologica

authors： Vitale G,Cascone E,Lupoli G Jr,Ciccarelli A,Barone C,Lupoli G

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare the diagnostic accuracy of fine needle biopsy (FNB) and intraoperative frozen-section biopsy (FS) regarding the surgical management of thyroid nodules. METHODS:A total of 812 patients with solitary nodule or dominant nodule in a multinodular goiter were evaluated. The pa...

journal_title：Minerva endocrinologica

authors： Morosini PP,Mancini V,Filipponi S,Taccaliti A,Ferretti M,Gusella P,Vecchi A,Fianchini A,Fabris G

更新日期：1997-03-01 00:00:00

abstract：:The treatment of NIDDM patients with secondary failure to sulfonylureas is still a debated problem. In this study we compared in NIDDM patients with secondary failure to glyburide, the effect of adding a single, low-dose bed time either NPH or ultralent insulin injection (0.15-0.2 U/kg) to the previously ineffective s...

journal_title：Minerva endocrinologica

authors： Sangiorgio L,Rabuazzo MA,Cordaro G,Grasso G,Condorelli L,Lunetta M

更新日期：1996-06-01 00:00:00

abstract：:The present insulin preparations are not ideal for diabetes therapy by subcutaneous administration, subcutaneous insulin absorption is too slow to mimic the normal rapid increments of insulin in blood in response to nutrient intake. The absorption of insulin from subcutaneous tissue is influenced by many factors, amon...

journal_title：Minerva endocrinologica

authors： Scaglione L,Cavallo-Perin P

更新日期：1996-03-01 00:00:00

abstract：:Visualization of cerebral perfusion with Single Photon Emission Computed Tomography (SPET) needs lipophil radiotracers which are able to cross the intact blood-brain-barrier (BBB); moreover local uptake must reflect regional cerebral blood flow. In the last decade many radiopharmaceuticals have been suggested and empl...

journal_title：Minerva endocrinologica

authors： Orsolon P,Bagni B,Cattaruzzi E,Englaro E,Guerra UP

更新日期：1995-12-01 00:00:00

abstract：:Adrenal scintigraphy using 131I-6-beta-iodomethyl-19-norcholesterol or 6-methyl-75Se-methyl-19-norcholesterol is a function-dependent imaging method which, in association with high-resolution spatial imaging techniques, plays an essential role in the study of adrenocortical hyperfunction. It can distinguish between bi...

journal_title：Minerva endocrinologica

authors： Gregianin M,Bui F,Varotto L,Zucchetta P,Macri C

更新日期：1995-03-01 00:00:00

abstract：:Adrenals are a common site of metastasis for many solid tumors. Adrenal metastases, and related symptoms of adrenal failure, are usually overlooked in clinical practice. This is probably due to the functional compensation of the adrenal glands and to the fact that signs and symptoms of adrenal insufficiency are aspeci...

journal_title：Minerva endocrinologica

authors： Piga A,Bracci R,Porfiri E,Cellerino R

更新日期：1995-03-01 00:00:00

abstract：:Primary hyperparathyroidism is a not uncommon disease in the elderly. A prevalence of 3% for women and 1% for men is reported in subjects aged 65 years and over. Routine serum calcium determination and parathyroid hormone radioimmuno-assay allow to make an early diagnosis in still asymptomatic subjects. In the elderly...

journal_title：Minerva endocrinologica

authors： Molaschi M,Ponzetto M,Romin R,Cerrato P,Gangemi D

更新日期：1994-12-01 00:00:00

abstract：:Diabetological care in pre-gestational (preGDM) and gestational (GDM) pregnant diabetic is an indispensable factor for the reduction of risk of mother, fetus and newborn complications. The adoption of an intensified therapy, aiming at maintaining almost normal glycemic values, and the improvement in fetal monitoring h...

journal_title：Minerva endocrinologica

authors： Dradi Maraldi C,Santini C

更新日期：1994-06-01 00:00:00

abstract：:The pathogenesis of Polycystic Ovary Syndrome (PCOs) is not well known till now. Previous reports indicated an hyperinsulinemia and insulin resistance in obese and non obese PCOs. However the role of hyperinsulinemia in PCOs pathogenesis is not completely understood. In this study we evaluated the glycemic and insulin...

journal_title：Minerva endocrinologica

authors： Vagiri D,Barletta C,Cioli I,Scavo D

更新日期：1994-03-01 00:00:00

abstract：:We treated with PEI 81 patients carriers of autonomous thyroid nodule, 65 toxic and 16 non toxic, all with undetectable serum TSH and suppressed extranodular tissue on scintigraphy. The treatment schedule was: 1-2 sessions per week, 1-8 ml per session, 3-13 sessions in total, In relation to the size and the therapeuti...

journal_title：Minerva endocrinologica

authors： Livraghi T,Ferrari C,Paracchi A,Reschini E,Macchi RM,Ciocia GL,Pirola P

更新日期：1993-12-01 00:00:00

abstract：:Thyroid nodule is extremely common. Its prevalence has been estimated to be more than 5% in the adult population. If thyroid nodule is a rare condition, 0.004% a year, identifying those nodules, which are likely to be malignant, is very important for physicians. The evaluation of thyroid is carried out using the fine ...

journal_title：Minerva endocrinologica

authors： Danese D,Sciacchitano S

更新日期：1993-09-01 00:00:00

abstract：:Previous studies have shown a significant but weak correlation between speed of sound (SOS) and broadband ultrasound attenuation (BUA) in bone, and densitometric bone measurements. These findings indicate that these techniques reflect different properties of bone. We measured SOS and BUA in the os calcis (Achilles, Lu...

journal_title：Minerva endocrinologica

authors： Agnusdei D,Cepollaro C,Camporeale A,Gennari C

更新日期：1992-10-01 00:00:00

abstract：:To investigate whether inappropriate LH secretion in Polycystic Ovary Syndrome (PCO) was related to a reduction of inhibitory opioid control on the GnRH-LH system, 23 women affected by PCO (12 obese, BMI: 37.1 +/- 3.9 and 11 non obese, BMI: 21.5 + 2.4) and 19 fertile women (10 obese, BMI: 38.8 + 1.8 and 9 non obese, B...

journal_title：Minerva endocrinologica

authors： Barletta C,Vagiri D,Scavo D

更新日期：1992-07-01 00:00:00